Anti-Tetanus Toxoid antibody [5.1B8],Abcam,AB26247

C. tetani toxoid injected in mice is not neutralized efficiently enough by administration of this antibody to allow rescue.

Host

Mouse

Reactivity

Clostridium tetani

Application

ELISA

Platform ID

BAB990558770

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Tetanus Toxoid antibody [5.1B8]
Cat. No.AB26247
HostMouse
IsotypeIgG1
ReactivityClostridium tetani
ApplicationELISA
ClonalityMonoclonal
Clone Number5.1B8
Concentration1.05 mg/mL Batch dependent concentration
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.097% Sodium azide Constituents: PBS, 2.9% Sodium chloride
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-|-Phe-77' bond of synaptobrevin-2. See full target information tetX

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