Anti-Tetanus Toxoid antibody,Abcam,AB24292

Host

Goat

Reactivity

Clostridium tetani

Application

Ie

Platform ID

BAB303065017

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Tetanus Toxoid antibody
Cat. No.AB24292
HostGoat
IsotypeIgG
ReactivityClostridium tetani
ApplicationIe
ClonalityPolyclonal
Concentration5 mg/mL Batch dependent concentration
PurityIon exchange chromatography
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.1% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-|-Phe-77' bond of synaptobrevin-2. See full target information tetX

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