Anti-Thymidylate Synthase antibody [TYMS/1884],Abcam,AB224649

Host

Mouse

Reactivity

Human

Application

Protein Array, ICC, WB, Flow Cyt, IHC-P

Platform ID

BAB367745220

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Thymidylate Synthase antibody [TYMS/1884]
Cat. No.AB224649
HostMouse
IsotypeIgG2a
ReactivityHuman
ApplicationProtein Array, ICC, WB, Flow Cyt, IHC-P
ClonalityMonoclonal
Clone NumberTYMS/1884
Concentration0.2 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human TYMS aa 50-200. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A/G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Catalyzes the reductive methylation of 2'-deoxyuridine 5'-monophosphate (dUMP) to thymidine 5'-monophosphate (dTMP), using the cosubstrate, 5,10- methylenetetrahydrofolate (CH2H4folate) as a 1-carbon donor and reductant and contributes to the de novo mitochondrial thymidylate biosynthesis pathway. See full target information TYMS

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