Anti-Tissue Plasminogen Activator antibody [629.2A1.53],Abcam,AB27418

Host

Mouse

Reactivity

Human

Application

ELISA, WB

Platform ID

BAB994756754

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Tissue Plasminogen Activator antibody [629.2A1.53]
Cat. No.AB27418
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationELISA, WB
ClonalityMonoclonal
Clone Number629.2A1.53
Concentration1.9 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human PLAT.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 6.6 Constituents: 0.82% Sodium phosphate, 0.58% Sodium chloride, 0.0292% EDTA
Storage-80°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. During oocyte activation, plays a role in cortical granule reaction in the zona reaction, which contributes to the block to polyspermy (By similarity). See full target information PLAT

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