Anti-Tissue Plasminogen Activator antibody,Abcam,AB62763

The concentration of this antibody is lot specific.

Host

Rabbit

Reactivity

Mouse, Rat

Application

ELISA, WB

Platform ID

BAB244781742

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Tissue Plasminogen Activator antibody
Cat. No.AB62763
HostRabbit
IsotypeIgG
ReactivityMouse, Rat
ApplicationELISA, WB
ClonalityPolyclonal
Concentration8.09 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Mouse Plat.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationConstituents: 0.82% Sodium phosphate, 0.58% Sodium chloride, 0.0292% EDTA
Storage-80°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. During oocyte activation, plays a role in cortical granule reaction in the zona reaction, which contributes to the block to polyspermy (By similarity). See full target information Plat

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.