Anti-Tissue Plasminogen Activator antibody,Abcam,AB48649

Host

Sheep

Reactivity

Human

Application

IP, RIA, ELISA, EIA, WB

Platform ID

BAB932275495

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Tissue Plasminogen Activator antibody
Cat. No.AB48649
HostSheep
IsotypeIgG
ReactivityHuman
ApplicationIP, RIA, ELISA, EIA, WB
ClonalityPolyclonal
Concentration0.3 - 0.4 mg/mL Batch dependent concentration
ImmunogenNative Full Length Protein corresponding to Human PLAT.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.5 Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. During oocyte activation, plays a role in cortical granule reaction in the zona reaction, which contributes to the block to polyspermy (By similarity). See full target information PLAT

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.