Anti-Tissue Plasminogen Activator antibody [H27B6],Abcam,AB28374

Host

Mouse

Reactivity

Rat, Mouse

Application

ELISA, WB, IHC-P

Platform ID

BAB432325471

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Tissue Plasminogen Activator antibody [H27B6]
Cat. No.AB28374
HostMouse
IsotypeIgG
ReactivityRat, Mouse
ApplicationELISA, WB, IHC-P
ClonalityMonoclonal
Clone NumberH27B6
Concentration1.1 - 4.35 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Mouse Plat.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Constituents: 0.87% Sodium chloride, 0.82% Sodium phosphate
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. During oocyte activation, plays a role in cortical granule reaction in the zona reaction, which contributes to the block to polyspermy (By similarity). See full target information Plat

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