Anti-Topoisomerase II beta/TOP2B antibody,Abcam,AB235898

Host

Rabbit

Reactivity

Human

Application

IHC-P, ICC/IF

Platform ID

BAB248180110

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Topoisomerase II beta/TOP2B antibody
Cat. No.AB235898
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIHC-P, ICC/IF
ClonalityPolyclonal
Concentration1 - 2.7 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human DNA topoisomerase 2-beta aa 1400 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand. Plays a role in B-cell differentiation. See full target information DNA topoisomerase 2-beta

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