Anti-Topoisomerase II beta/TOP2B antibody,Abcam,AB264158

Host

Rabbit

Reactivity

Mouse, Human

Application

IP, IHC-P, WB

Platform ID

BAB560686357

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Topoisomerase II beta/TOP2B antibody
Cat. No.AB264158
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationIP, IHC-P, WB
ClonalityPolyclonal
Concentration0.2 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human DNA topoisomerase 2-beta aa 1550 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 6.8 - 7.4 Preservative: 0.09% Sodium azide Constituents: Tris buffered saline, 0.1% BSA
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand. Plays a role in B-cell differentiation. See full target information DNA topoisomerase 2-beta

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