Anti-Transcription factor AP-2-alpha antibody [EPR2688(2)],Abcam,AB108311
What is this antibody validated in? Anti-Transcription factor AP-2-alpha antibody [EPR2688(2)] (ab108311) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) and ChIC/CUT&RUN sequencing in Human, Mouse, Rat samples. What is the molecular weight of Transcription factor AP-2-alpha? Anti-Transcription factor AP-2-alpha [EPR2688(2)] (ab108311) specifically detects a band for Transcription factor AP-2-alpha (UniProt: P05549) at a molecular weight of 48kDa. Trusted by the scientific community Anti-Transcription factor AP-2-alpha [EPR2688(2)] (ab108311) was first used in a scientific publication in 2011 and has been cited over 20 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 20µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-Transcription factor AP-2-alpha antibody [EPR2688(2)] (ab108311) has been confirmed by Western blot testing in TFAP2A Knockout HAP1 cell line, ab265122 . Other related products We have a range of other formats of antibody clone [EPR2688(2)] also available for your convenience: ab108311, Carrier free - ab236043 , PE - ab305403 , APC - ab305404 , HRP - ab305405 , Alkaline Phosphatase - ab309016 , Alexa Fluor® 488 - ab309663 , Alexa Fluor® 647 - ab310026 , Alexa Fluor® 594 - ab310404 , Alexa Fluor® 555 - ab311931 , Alexa Fluor® 568 - ab312402 , Alexa Fluor® 750 - ab320892 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
IHC-P, Flow Cyt (Intra), WB, ICC/IF, IP, ChIC/CUT&RUN-seq
Platform ID
BAB499504474
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region. See full target information TFAP2A
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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