Anti-Tropomodulin 1 antibody,Abcam,AB230276

Host

Rabbit

Reactivity

Mouse, Human

Application

WB, IHC-P

Platform ID

BAB564684437

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Tropomodulin 1 antibody
Cat. No.AB230276
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationWB, IHC-P
ClonalityPolyclonal
Concentration0.32 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human TMOD1.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.3 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Blocks the elongation and depolymerization of the actin filaments at the pointed end (PubMed : 38168645). The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus. See full target information TMOD1

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