Anti-Tyrosinase antibody [OCA1/812],Abcam,AB216023
Host
Mouse
Reactivity
Human
Application
IHC-P
Platform ID
BAB567483093
Abcam
Contact
Tel: +44 (0)1223 696000
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Product Specifications
Scientific Background
Specifications
NameAnti-Tyrosinase antibody [OCA1/812]
Cat. No.AB216023
HostMouse
IsotypeIgG2a
ReactivityHuman
ApplicationIHC-P
ClonalityMonoclonal
Clone NumberOCA1/812
Concentration0.2 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human Tyrosinase.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine (By similarity). In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone (PubMed : 28661582). See full target information Tyrosinase
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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