Anti-Tyrosine Hydroxylase antibody - Neuronal Marker,Abcam,AB76442

Anti-Tyrosine Hydroxylase antibody (ab76442) is a chicken polyclonal antibody and is validated for use in IHC-FrFl, IHC-P in rat samples. Anti-Tyrosine Hydroxylase antibody (ab76442) has been cited over 160 times in peer reviewed journals and is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-Tyrosine Hydroxylase antibody (ab76442) has high sensitivity and specificity. Anti-Tyrosine Hydroxylase antibody (ab76442) has 12 independent reviews from customers. Anti-Tyrosine Hydroxylase antibody (ab76442) specifically detects Tyrosine Hydroxylase (UniProt ID: P07101; Molecular weight: 59kDa) and is sold in 250 µL selling sizes.

Host

Chicken

Reactivity

Mouse

Application

IHC-FrFl, IHC-P

Platform ID

BAB130114280

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Tyrosine Hydroxylase antibody - Neuronal Marker
Cat. No.AB76442
HostChicken
IsotypeIgY
ReactivityMouse
ApplicationIHC-FrFl, IHC-P
ClonalityPolyclonal
Concentration0.2 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human TH conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.02% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Catalyzes the conversion of L-tyrosine to L-dihydroxyphenylalanine (L-Dopa), the rate-limiting step in the biosynthesis of catecholamines, dopamine, noradrenaline, and adrenaline. Uses tetrahydrobiopterin and molecular oxygen to convert tyrosine to L-Dopa (PubMed : 15287903, PubMed : 1680128, PubMed : 17391063, PubMed : 24753243, PubMed : 34922205, PubMed : 8528210, Ref.18). In addition to tyrosine, is able to catalyze the hydroxylation of phenylalanine and tryptophan with lower specificity (By similarity). Positively regulates the regression of retinal hyaloid vessels during postnatal development (By similarity).. Isoform 5. Lacks catalytic activity.. Isoform 6. Lacks catalytic activity. See full target information TH

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.