Anti-UBASH3A antibody,Abcam,AB197168
Host
Rabbit
Reactivity
Human
Application
IHC-P, WB
Platform ID
BAB880489100
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
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Product Specifications
Scientific Background
Specifications
NameAnti-UBASH3A antibody
Cat. No.AB197168
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIHC-P, WB
ClonalityPolyclonal
ImmunogenRecombinant Fragment Protein within Human UBASH3A aa 100-350. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLyophilized
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. Exhibits negligible protein tyrosine phosphatase activity at neutral pH. May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain. See full target information UBASH3A
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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