Anti-UFC1 antibody [EPR15014-102],Abcam,AB189252

Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Human

Application

IP, IHC-P, WB

Platform ID

BAB006750994

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-UFC1 antibody [EPR15014-102]
Cat. No.AB189252
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIP, IHC-P, WB
ClonalityMonoclonal
Clone NumberEPR15014-102
Concentration1.953 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data E2-like enzyme which specifically catalyzes the second step in ufmylation (PubMed : 15071506, PubMed : 29868776, PubMed : 30626644, PubMed : 34588452, PubMed : 35394863, PubMed : 36121123, PubMed : 38383789). Accepts the ubiquitin-like modifier UFM1 from the E1 enzyme UBA5 and forms an intermediate with UFM1 via a thioester linkage (PubMed : 15071506, PubMed : 29868776, PubMed : 34588452, PubMed : 38383789). Ufmylation is involved in various processes, such as ribosome recycling, response to DNA damage, interferon response or reticulophagy (also called ER-phagy) (PubMed : 27351204, PubMed : 32160526, PubMed : 35394863, PubMed : 37036982, PubMed : 38383789). See full target information UFC1

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