Anti-UGDH antibody,Abcam,AB246999

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

IHC-P, WB, ICC/IF

Platform ID

BAB006850946

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-UGDH antibody
Cat. No.AB246999
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationIHC-P, WB, ICC/IF
ClonalityPolyclonal
Concentration0.08 - 0.1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human UDP-glucose 6-dehydrogenase aa 400 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Catalyzes the formation of UDP-alpha-D-glucuronate, a constituent of complex glycosaminoglycans (PubMed : 21502315, PubMed : 21961565, PubMed : 22123821, PubMed : 23106432, PubMed : 25478983, PubMed : 27966912, PubMed : 30420606, PubMed : 30457329). Required for the biosynthesis of chondroitin sulfate and heparan sulfate. Required for embryonic development via its role in the biosynthesis of glycosaminoglycans (By similarity). Required for proper brain and neuronal development (PubMed : 32001716). See full target information UDP-glucose 6-dehydrogenase

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