Anti-USP1 antibody,Abcam,AB84772
Host
Rabbit
Reactivity
Human
Application
IHC-P
Platform ID
BAB070831485
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
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Product Specifications
Scientific Background
Specifications
NameAnti-USP1 antibody
Cat. No.AB84772
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIHC-P
ClonalityPolyclonal
ImmunogenSynthetic Peptide within Human Ubiquitin carboxyl-terminal hydrolase 1 aa 450-500. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 6.8 - 7.4 Preservative: 0.09% Sodium azide Constituents: Tris buffered saline, 0.1% BSA
Storage+4°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2 (PubMed : 15694335). Also involved in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA (PubMed : 16531995, PubMed : 20147293). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity (PubMed : 18082604, PubMed : 26388029). See full target information Ubiquitin carboxyl-terminal hydrolase 1
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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