Anti-USP46 antibody [CL0364],Abcam,AB244215

Host

Mouse

Reactivity

Human

Application

ICC/IF, WB

Platform ID

BAB008849986

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-USP46 antibody [CL0364]
Cat. No.AB244215
HostMouse
IsotypeIgG2a
ReactivityHuman
ApplicationICC/IF, WB
ClonalityMonoclonal
Clone NumberCL0364
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human USP46 aa 100-250. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67 (By similarity). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity (PubMed : 19075014, PubMed : 26388029). Not involved in deubiquitination of monoubiquitinated FANCD2 (PubMed : 19075014). See full target information USP46

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