Anti-VAP1 antibody [174-5],Abcam,AB81718

This antibody inhibits lymphocyte infiltration in liver allograft rejection in rats.

Host

Mouse

Reactivity

Human

Application

IHC-Fr

Platform ID

BAB196993427

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-VAP1 antibody [174-5]
Cat. No.AB81718
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationIHC-Fr
ClonalityMonoclonal
Clone Number174-5
Concentration0.1 mg/mL Batch dependent concentration
ImmunogenTissue preparation containing AOC3 protein. The exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationConstituents: PBS, 0.1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia (PubMed : 19588076, PubMed : 24304424, PubMed : 9653080). Has a preference for the primary monoamines methylamine and benzylamine (PubMed : 19588076, PubMed : 9653080). Could also act on 2-phenylethylamine but much less efficiently (PubMed : 19588076). At endothelial cells surface can also function as a cell adhesion protein that participates in lymphocyte extravasation and recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion (PubMed : 9254657, PubMed : 9653080).. Isoform 2. Has no semicarbazide-sensitive amine oxidase (SSAO) activity. See full target information AOC3

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