Anti-VAP1 antibody,Abcam,AB115574

Host

Goat

Reactivity

Human

Application

IHC-P

Platform ID

BAB822005921

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-VAP1 antibody
Cat. No.AB115574
HostGoat
IsotypeIgG
ReactivityHuman
ApplicationIHC-P
ClonalityPolyclonal
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human AOC3 aa 700-750. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.3 Preservative: 0.02% Sodium azide Constituents: 99% Tris buffered saline, 0.5% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia (PubMed : 19588076, PubMed : 24304424, PubMed : 9653080). Has a preference for the primary monoamines methylamine and benzylamine (PubMed : 19588076, PubMed : 9653080). Could also act on 2-phenylethylamine but much less efficiently (PubMed : 19588076). At endothelial cells surface can also function as a cell adhesion protein that participates in lymphocyte extravasation and recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion (PubMed : 9254657, PubMed : 9653080).. Isoform 2. Has no semicarbazide-sensitive amine oxidase (SSAO) activity. See full target information AOC3

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