Anti-VAX2 antibody [VAX2A8F12],Abcam,AB50899
Host
Mouse
Reactivity
Mouse, Human
Application
WB, ICC/IF
Platform ID
BAB259974446
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
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Product Specifications
Scientific Background
Specifications
NameAnti-VAX2 antibody [VAX2A8F12]
Cat. No.AB50899
HostMouse
IsotypeIgG1
ReactivityMouse, Human
ApplicationWB, ICC/IF
ClonalityMonoclonal
Clone NumberVAX2A8F12
Concentration0.1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human VAX2. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Transcription factor that may function in dorsoventral specification of the forebrain. Regulates the expression of Wnt signaling antagonists including the expression of a truncated TCF7L2 isoform that cannot bind CTNNB1 and acts therefore as a potent dominant-negative Wnt antagonist. Plays a crucial role in eye development and, in particular, in the specification of the ventral optic vesicle (By similarity). May be a regulator of axial polarization in the retina. See full target information VAX2
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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