Anti-VCAM1 antibody [EPR5047],Abcam,AB134047
Anti-VCAM1 antibody [EPR5047] (ab134047) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), I-ELISA, ICC/IF, IHC-P, IP and WB. Anti-VCAM1 antibody [EPR5047] (ab134047) was first used in a scientific publication in 2013 and has been cited over 309 times in peer reviewed journals. It's performance in Western Blot and IHC in mouse and human samples is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-VCAM1 antibody [EPR5047] (ab134047) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-VCAM1 antibody [EPR5047] (ab134047) has been confirmed by Western Blot testing in VCAM1 knockout A549 cells ( ab273758 ). Anti-VCAM1 antibody [EPR5047] (ab134047) has 16 independent reviews from customers. Anti-VCAM1 antibody [EPR5047] (ab134047) specifically detects VCAM1 (UniProt ID: P29533; Molecular weight: 79kDa) and is sold in 100 µL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EPR5047 - ab215380 . Antibody clone EPR5047 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor ® 647, HRP, PE, FITC, APC ( ab194319 , ab195540 , ab223981 , ab223982 , ab223983 ). - Specificity confirmed with SYP knockout cell line validation Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
ICC/IF, IP, WB, IHC-P, I-ELISA, Flow Cyt (Intra)
Platform ID
BAB635061904

Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Cell adhesion glycoprotein predominantly expressed on the surface of endothelial cells that plays an important role in immune surveillance and inflammation (PubMed : 31310649). Acts as a major regulator of leukocyte adhesion to the endothelium through interaction with different types of integrins (PubMed : 10209034). During inflammatory responses, binds ligands on the surface of activated endothelial cells to initiate the activation of calcium channels and the plasma membrane-associated small GTPase RAC1 leading to leukocyte transendothelial migration (PubMed : 22970700). Also serves as a quality-control checkpoint for entry into bone marrow by providing a 'don't-eat-me' stamping in the context of major histocompatibility complex (MHC) class-I presentation (PubMed : 35210567). See full target information VCAM1
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
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