Anti-VDAC1/Porin antibody [16G9E6BC4] - Mitochondrial Loading Control,Abcam,AB110326

Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]

Host

Mouse

Reactivity

Saccharomyces cerevisiae

Application

WB

Platform ID

BAB697643115

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-VDAC1/Porin antibody [16G9E6BC4] - Mitochondrial Loading Control
Cat. No.AB110326
HostMouse
IsotypeIgG1
ReactivitySaccharomyces cerevisiae
ApplicationWB
ClonalityMonoclonal
Clone Number16G9E6BC4
Concentration1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.5 Preservative: 0.02% Sodium azide Constituents: HEPES buffered saline
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Non-selective voltage-gated ion channel that mediates the transport of anions and cations through the mitochondrion outer membrane (PubMed : 9435273). The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV (PubMed : 9435273). The open state has a weak anion selectivity whereas the closed state is cation-selective (PubMed : 9435273). Is the major permeability factor of the mitochondrial outer membrane (PubMed : 9435273).. Catalyzes the scrambling of phospholipids across the outer mitochondrial membrane; the mechanism is unrelated to channel activity and is capable of translocating both anionic and zwitterionic phospholipids. See full target information POR1

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