Anti-VE Cadherin antibody [EPR18229] - Intercellular Junction Marker,Abcam,AB205336
What is this antibody validated in? Anti-VE Cadherin antibody [EPR18229] - Intercellular Junction Marker (ab205336) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP), Immunocytochemistry/immunofluorescence (ICC/IF) in Mouse samples. What is the molecular weight of VE Cadherin? Anti-VE Cadherin [EPR18229] - Intercellular Junction Marker (ab205336) specifically detects a band for VE Cadherin (UniProt: P55284) at a molecular weight of 88kDa. Trusted by the scientific community Anti-VE Cadherin [EPR18229] - Intercellular Junction Marker (ab205336) was first used in a scientific publication in 2015 and has been cited over 40 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EPR18229] also available for your convenience: ab205336, Alexa Fluor® 647 - ab225442 , Alexa Fluor® 488 - ab225443 , Carrier free - ab232515 , Carrier free - ab242594 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse
Application
WB, ICC/IF, IP
Platform ID
BAB510299290
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Cadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity). This cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions (PubMed : 20332120, PubMed : 9220534). It associates with alpha-catenin forming a link to the cytoskeleton (By similarity). Plays a role in coupling actin fibers to cell junctions in endothelial cells, via acting as a cell junctional complex anchor for AMOTL2 and MAGI1 (PubMed : 24806444). Acts in concert with KRIT1 and PALS1 to establish and maintain correct endothelial cell polarity and vascular lumen (PubMed : 27466317). These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B (By similarity). Required for activation of PRKCZ and for localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction (By similarity). See full target information Cdh5
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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