Anti-VEGFA antibody [EP1176Y] - C-terminal,Abcam,AB52917
Abcam recommended secondaries - Goat Anti-Rabbit HRP ( ab205718 ) and Goat Anti-Rabbit Alexa Fluor® 488 ( ab150077 ). Or search our wide range of secondary antibodies for use with your experiment. Product Specifications Anti-VEGFA antibody [EP1176Y] - C-terminal (ab52917) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-P in human, mouse samples. Anti-VEGFA antibody [EP1176Y] - C-terminal (ab52917) specifically detects VEGFA (UniProt ID: P15692; Molecular weight: 44kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Quality and Validation Abcam's high quality manufacturing and validation processes ensure Anti-VEGFA antibody [EP1176Y] - C-terminal (ab52917) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-VEGFA antibody [EP1176Y] - C-terminal (ab52917) has been cited over 221 times in peer reviewed journals and is trusted by the scientific community. Anti-VEGFA antibody [EP1176Y] - C-terminal (ab52917) has 9 independent reviews from customers. Related Products Conjugation-ready, carrier free format available for antibody clone EP1176Y - ab212816 . Antibody clone EP1176Y is also available pre-conjugated to a variety of labels for your convenience - Biotin, Alexa Fluor® 488, Alexa Fluor® 647, Alexa Fluor® 594, PE ( ab195902 , ab206886 , ab206887 , ab206888 , ab209439 ). Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Human
Application
Flow Cyt (Intra), IHC-P, ICC/IF
Platform ID
BAB823305297
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data N-VEGF. Participates in the induction of key genes involved in the response to hypoxia and in the induction of angiogenesis such as HIF1A (PubMed : 35455969). Involved in protecting cells from hypoxia-mediated cell death (By similarity).. VEGFA. Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth (PubMed : 34530889). Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Binds to the NRP1/neuropilin-1 receptor. Binding to NRP1 initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By similarity). Also binds the DEAR/FBXW7-AS1 receptor (PubMed : 17446437).. Isoform VEGF165B. Binds to the KDR receptor but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. See full target information VEGFA
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
- Products>Trial Size Antibodies
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