Anti-VEGFA antibody [VG-1],Abcam,AB1316
Product Specifications Anti-VEGFA antibody [VG-1] (ab1316) is a mouse monoclonal antibody and is validated for use in IHC-P in human, mouse, rat samples. Anti-VEGFA antibody [VG-1] (ab1316) specifically detects VEGFA (UniProt ID: P15692; Molecular weight: 44kDa) and is sold in 100 µg selling sizes. Quality and Validation Abcam's high quality validation processes ensure Anti-VEGFA antibody [VG-1] (ab1316) has high sensitivity and specificity. Anti-VEGFA antibody [VG-1] (ab1316) has been cited over 383 times in peer reviewed journals and is trusted by the scientific community. Anti-VEGFA antibody [VG-1] (ab1316) has 44 independent reviews from customers. Related Products Conjugation-ready, carrier free format available for antibody clone VG-1 - ab239882 . Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]
Host
Mouse
Reactivity
Mouse, Rat, Human
Application
IHC-P
Platform ID
BAB635861520
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data N-VEGF. Participates in the induction of key genes involved in the response to hypoxia and in the induction of angiogenesis such as HIF1A (PubMed : 35455969). Involved in protecting cells from hypoxia-mediated cell death (By similarity).. VEGFA. Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth (PubMed : 34530889). Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Binds to the NRP1/neuropilin-1 receptor. Binding to NRP1 initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By similarity). Also binds the DEAR/FBXW7-AS1 receptor (PubMed : 17446437).. Isoform VEGF165B. Binds to the KDR receptor but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. See full target information VEGFA
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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