Anti-Vimentin antibody,Abcam,AB137321
Anti-Vimentin antibody (ab137321) is a rabbit polyclonal antibody and is validated for use in ICC/IF, IHC-P, IP, WB in chicken, chinese hamster, cow, dog, human, mouse, rat samples. Anti-Vimentin antibody (ab137321) has been cited over 257 times in peer reviewed journals and is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-Vimentin antibody (ab137321) has high sensitivity and specificity. Anti-Vimentin antibody (ab137321) specifically detects Vimentin protein (UniProt ID: P08670; Molecular weight: 54kDa) and is sold in 50 µL selling sizes. Vimentin is a type of intermediate filament protein that plays a significant role in cancer biology. It is commonly used as a marker for epithelial-mesenchymal transition (EMT), a process where epithelial cells acquire mesenchymal properties, which is crucial for cancer metastasis. Vimentin is often overexpressed in various types of cancers and its overexpression is associated with increased tumor growth, invasion, and poor prognosis.
Host
Rabbit
Reactivity
Mouse, Rat, Chicken, Dog, Human
Application
WB, ICC/IF, IHC-P, IP
Platform ID
BAB449017455
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-Vimentin antibody
Cat. No.AB137321
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Chicken, Dog, Human
ApplicationWB, ICC/IF, IHC-P, IP
ClonalityPolyclonal
Concentration0.15 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human VIM. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.025% Proclin 300 Constituents: PBS, 20% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Vimentin, a class-III intermediate filament, is present in various non-epithelial cells, particularly mesenchymal cells, and connects either laterally or terminally to the nucleus, endoplasmic reticulum, and mitochondria. It is involved with LARP6 in stabilizing type I collagen mRNAs for CO1A1 and CO1A2. This supplementary information is collated from multiple sources and compiled automatically. See full target information VIM
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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