Anti-Vimentin antibody [SP20], prediluted,Abcam,AB27608

Host

Rabbit

Reactivity

Human

Application

IHC-P, WB, ICC/IF, Flow Cyt

Platform ID

BAB074129901

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Vimentin antibody [SP20], prediluted
Cat. No.AB27608
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIHC-P, WB, ICC/IF, Flow Cyt
ClonalityMonoclonal
Clone NumberSP20
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.6 Preservative: 0.1% Sodium azide Constituents: Tissue culture supernatant, Tris buffered saline, 1% BSA
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. Plays a role in cell directional movement, orientation, cell sheet organization and Golgi complex polarization at the cell migration front (By similarity). Protects SCRIB from proteasomal degradation and facilitates its localization to intermediate filaments in a cell contact-mediated manner (By similarity). May promote axon outgrowth and motor fiber repair via DSP-mediated recruitment to outgrowth tips (By similarity).. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. See full target information VIM

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