Anti-WISP1 antibody - C-terminal,Abcam,AB178547

Host

Rabbit

Reactivity

Rat, Human, Mouse

Application

IHC-Fr, WB, IHC-FoFr

Platform ID

BAB327153449

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-WISP1 antibody - C-terminal
Cat. No.AB178547
HostRabbit
IsotypeIgG
ReactivityRat, Human, Mouse
ApplicationIHC-Fr, WB, IHC-FoFr
ClonalityPolyclonal
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human CCN4 aa 350 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationConstituents: 76.92% Trehalose, 17.31% Sodium chloride, 3.85% Disodium hydrogenorthophosphate
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan. See full target information CCN4

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