Anti-Wilms Tumor Protein antibody [CAN-R9(IHC)-56-2],Abcam,AB89901
Anti-Wilms Tumor Protein antibody [CAN-R9(IHC)-56-2] (ab89901) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-P and WB. Anti-Wilms Tumor Protein antibody [CAN-R9(IHC)-56-2] (ab89901) was first used in a scientific publication in 2011 and has been cited over 252 times in peer reviewed journals. It's performance in IHC in mouse and human samples is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-Wilms Tumor Protein antibody [CAN-R9(IHC)-56-2] (ab89901) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-Wilms Tumor Protein antibody [CAN-R9(IHC)-56-2] (ab89901) has 40 independent reviews from customers. Anti-Wilms Tumor Protein antibody [CAN-R9(IHC)-56-2] (ab89901) specifically detects Wilms Tumor Protein (UniProt ID: P19544; Molecular weight: 50kDa) and is sold in 100 µL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone CAN-R9(IHC)-56-2 - ab216646 . Antibody clone CAN-R9(IHC)-56-2 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor ® 488, Alexa Fluor ® 647, FITC, Alexa Fluor ® 555 ( ab202635 , ab202639 , ab223934 , ab314587 ). Wilms Tumor Protein (WT1) is a tumor-associated antigen that is overexpressed in various cancers, making it a target for immunotherapeutic approaches. It plays a role in tumor progression and immune evasion, influencing the tumor microenvironment and the effectiveness of immune responses. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Human
Application
Flow Cyt (Intra), WB, ICC/IF, IHC-P
Platform ID
BAB077028509
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Transcription factor that plays an important role in cellular development and cell survival (PubMed : 7862533). Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3' (PubMed : 17716689, PubMed : 25258363, PubMed : 7862533). Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific : isoforms lacking the KTS motif may act as transcription factors (PubMed : 15520190). Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing (PubMed : 16934801). Isoform 1 has lower affinity for DNA, and can bind RNA (PubMed : 19123921). See full target information WT1
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
- Products>Trial Size Antibodies
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