Anti-Wnt1 antibody,Abcam,AB63934

This product is manufactured by BioVision, an Abcam company and was previously called 3571 Anti-Wnt-1 Antibody. 3571-100 is the same size as the 100 µg size of ab63934. Wnt1 antibody has been purified by Protein A/G combination.

Host

Rabbit

Reactivity

Human

Application

WB

Platform ID

BAB077328365

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Wnt1 antibody
Cat. No.AB63934
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationWB
ClonalityPolyclonal
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human WNT1. The exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 30% Glycerol (glycerin, glycerine), 0.5% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation (PubMed : 23499309, PubMed : 23656646, PubMed : 26902720, PubMed : 28528193). In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling (By similarity). Plays an essential role in the development of the embryonic brain and central nervous system (CNS) (By similarity). Has a role in osteoblast function, bone development and bone homeostasis (PubMed : 23499309, PubMed : 23656646). See full target information WNT1

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