Anti-Wnt10a antibody,Abcam,AB106522

Host

Rabbit

Reactivity

Mouse, Human

Application

ICC/IF, WB, IHC-P

Platform ID

BAB389834612

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Wnt10a antibody
Cat. No.AB106522
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationICC/IF, WB, IHC-P
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human Protein Wnt-10a. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). Plays a role in normal ectoderm development (PubMed : 17847007, PubMed : 28589954). Required for normal tooth development (PubMed : 17847007, PubMed : 28589954, PubMed : 29178643). Required for normal postnatal development and maintenance of tongue papillae and sweat ducts (PubMed : 28589954). Required for normal proliferation of basal cells in tongue filiform papillae, plantar epithelium and sweat ducts. Required for normal expression of keratins in tongue papillae (By similarity). Required for normal expression of KRT9 in foot plant epithelium (PubMed : 28589954). Required for normal hair follicle function (PubMed : 28589954). See full target information Protein Wnt-10a

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