Anti-Wnt3a antibody,Abcam,AB169175

Host

Mouse

Reactivity

Human

Application

ICC/IF, WB

Platform ID

BAB702540763

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Wnt3a antibody
Cat. No.AB169175
HostMouse
IsotypeIgG
ReactivityHuman
ApplicationICC/IF, WB
ClonalityPolyclonal
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human WNT3A.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (PubMed : 20093360, PubMed : 21244856, PubMed : 24841207, PubMed : 26902720). Required for normal embryonic mesoderm development and formation of caudal somites. Required for normal morphogenesis of the developing neural tube (By similarity). Mediates self-renewal of the stem cells at the bottom on intestinal crypts (in vitro) (PubMed : 26902720). See full target information WNT3A

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