Anti-Wnt4 antibody [HL1889],Abcam,AB317117

Host

Rabbit

Reactivity

Human, Mouse, Zebrafish

Application

ICC/IF, WB

Platform ID

BAB890084492

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Wnt4 antibody [HL1889]
Cat. No.AB317117
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Zebrafish
ApplicationICC/IF, WB
ClonalityMonoclonal
Clone NumberHL1889
Concentration2 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human WNT4.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Plays an important role in the embryonic development of the urogenital tract and the lung (PubMed : 15317892, PubMed : 16959810, PubMed : 18179883, PubMed : 18182450). Required for normal mesenchyme to epithelium transition during embryonic kidney development. Required for the formation of early epithelial renal vesicles during kidney development (By similarity). Required for normal formation of the Mullerian duct in females, and normal levels of oocytes in the ovaries (PubMed : 15317892, PubMed : 16959810, PubMed : 18182450). Required for normal down-regulation of 3 beta-hydroxysteroid dehydrogenase in the ovary (PubMed : 15317892, PubMed : 16959810, PubMed : 18182450). Required for normal lung development and for normal patterning of trachael cartilage rings (By similarity). See full target information WNT4 Additional targets Wnt4,

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.