Anti-Xrn1 antibody,Abcam,AB70259
Host
Rabbit
Reactivity
Mouse, Human
Application
ICC/IF, WB, IP, EMSA
Platform ID
BAB141109000
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-Xrn1 antibody
Cat. No.AB70259
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationICC/IF, WB, IP, EMSA
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human XRN1. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 - 8 Preservative: 0.09% Sodium azide Constituents: PBS, 1.815% Tris, 1.764% Sodium citrate
Storage+4°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS). See full target information XRN1
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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