Anti-ZBTB1 antibody,Abcam,AB115170

Host

Rabbit

Reactivity

Mouse, Human

Application

WB

Platform ID

BAB142108520

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-ZBTB1 antibody
Cat. No.AB115170
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationWB
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human ZBTB1 aa 650 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 - 8 Preservative: 0.09% Sodium azide Constituents: 99% Tris citrate/phosphate
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Acts as a transcriptional repressor (PubMed : 20797634). Represses cAMP-responsive element (CRE)-mediated transcriptional activation (PubMed : 21706167). In addition, has a role in translesion DNA synthesis. Requires for UV-inducible RAD18 loading, PCNA monoubiquitination, POLH recruitment to replication factories and efficient translesion DNA synthesis (PubMed : 24657165). Plays a key role in the transcriptional regulation of T lymphocyte development (By similarity). See full target information ZBTB1

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