Anti-alpha 1 Antitrypsin antibody [EPR17087-50],Abcam,AB207303

What is this antibody validated in? Anti-alpha 1 Antitrypsin antibody [EPR17087-50] (ab207303) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human samples. What is the molecular weight of alpha 1 Antitrypsin? Anti-alpha 1 Antitrypsin [EPR17087-50] (ab207303) specifically detects a band for alpha 1 Antitrypsin (UniProt: P01009) at a molecular weight of 46kDa. Trusted by the scientific community Anti-alpha 1 Antitrypsin [EPR17087-50] (ab207303) was first used in a scientific publication in 2016 and has been cited over 10 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EPR17087-50] also available for your convenience: ab207303, Carrier free - ab240375 , HRP - ab309499 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Human

Application

IP, ICC/IF, IHC-P, WB

Platform ID

BAB949423582

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-alpha 1 Antitrypsin antibody [EPR17087-50]
Cat. No.AB207303
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIP, ICC/IF, IHC-P, WB
ClonalityMonoclonal
Clone NumberEPR17087-50
Concentration0.099 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.. Short peptide from AAT. Reversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. Its major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE). See full target information SERPINA1

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