Anti-alpha 1 Sodium Potassium ATPase antibody [464.6] - BSA and Azide free,Abcam,AB237969

This data was developed using the same antibody clone in a different buffer formulation containing PBS, L-arginine, and sodium azide (ab237969). Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]

Host

Mouse

Reactivity

Mouse, Rat, Rabbit, Human, Pig

Application

ICC/IF, IHC-P, WB

Platform ID

BAB449773414

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-alpha 1 Sodium Potassium ATPase antibody [464.6] - BSA and Azide free
Cat. No.AB237969
HostMouse
IsotypeIgG1
ReactivityMouse, Rat, Rabbit, Human, Pig
ApplicationICC/IF, IHC-P, WB
ClonalityMonoclonal
Clone Number464.6
Concentration1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationConstituents: PBS
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients (PubMed : 11738066). Could also be part of an osmosensory signaling pathway that senses body-fluid sodium levels and controls salt intake behavior as well as voluntary water intake to regulate sodium homeostasis (By similarity). See full target information ATP1A1

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