Anti-alpha 1 Sodium Potassium ATPase antibody [464.6] - Plasma Membrane Loading Control,Abcam,AB7671

Anti-alpha 1 Sodium Potassium ATPase antibody [464.6] (ab7671) is a House Mouse Monoclonal antibody and is validated for use in ICC/IF, IHC-P, WB in human, rat samples. Anti-alpha 1 Sodium Potassium ATPase antibody [464.6] (ab7671) has been cited over 357 times in peer reviewed journals and is trusted by the scientific community. Abcams high quality validation processes ensure Anti-alpha 1 Sodium Potassium ATPase antibody [464.6] (ab7671) has high sensitivity and specificity. Anti-alpha 1 Sodium Potassium ATPase antibody [464.6] (ab7671) has 41 independent reviews from customers. Anti-alpha 1 Sodium Potassium ATPase antibody [464.6] (ab7671) specifically detects alpha 1 Sodium Potassium ATPase (UniProt ID: Q9N0Z6; Molecular weight: 113kDa) and is sold in 100 ug selling sizes. Conjugation-ready, carrier free format available for antibody clone 464.6 - ab237969 . Antibody clone 464.6 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 647, HRP, Alexa Fluor® 488 ( ab196695 , ab196696 , ab197496 ). Alpha 1 Sodium Potassium ATPase (ATP1A1) is a critical enzyme involved in ion transport and maintaining electrolyte balance. The Na/K ATPase antibody (ATP1A1 antibody) is an essential tools for studying this enzyme's function. Abnormalities in ATP1A1 are linked to various diseases, including cardiovascular disorders and neurological conditions. Monitoring ATP1A1 levels can provide valuable insights into disease mechanisms and therapeutic targets. Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]

Host

Mouse

Reactivity

Mouse, Rat, Rabbit, Human, Pig

Application

ICC/IF, IHC-P, WB

Platform ID

BAB762279661

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-alpha 1 Sodium Potassium ATPase antibody [464.6] - Plasma Membrane Loading Control
Cat. No.AB7671
HostMouse
IsotypeIgG1
ReactivityMouse, Rat, Rabbit, Human, Pig
ApplicationICC/IF, IHC-P, WB
ClonalityMonoclonal
Clone Number464.6
Concentration1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 6.97% L-Arginine
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients (PubMed : 29499166, PubMed : 30388404). Could also be part of an osmosensory signaling pathway that senses body-fluid sodium levels and controls salt intake behavior as well as voluntary water intake to regulate sodium homeostasis (By similarity). See full target information ATP1A1

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