Anti-alpha 1a Adrenergic Receptor/ADRA1A antibody [S04-8B8],Abcam,AB317381

Host

Rabbit

Reactivity

Rat

Application

WB

Platform ID

BAB137367119

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-alpha 1a Adrenergic Receptor/ADRA1A antibody [S04-8B8]
Cat. No.AB317381
HostRabbit
IsotypeIgG
ReactivityRat
ApplicationWB
ClonalityMonoclonal
Clone NumberS04-8B8
ImmunogenSynthetic Peptide within Human ADRA1A.
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.01% Sodium azide Constituents: 55.08% Water, 40% Glycerol (glycerin, glycerine), 0.98% Tris glycine, 0.88% Sodium chloride, 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes (By similarity). See full target information Adra1a

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