Anti-alpha Defensin 5 antibody [EPR14309(B)] - BSA and Azide free,Abcam,AB245946
ab245946 is the carrier-free version of ab180515 . Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Conjugation ready Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications. Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold. Compatibility This product is compatible with the Maxpar ® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar ® is a trademark of Fluidigm Canada Inc.
Host
Rabbit
Reactivity
Human
Application
WB, IHC-P
Platform ID
BAB637916855
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Host-defense peptide that maintains sterility in the urogenital system (PubMed : 12021776, PubMed : 12660734, PubMed : 15616305, PubMed : 19589339, PubMed : 22359618, PubMed : 22573326, PubMed : 25354318, PubMed : 25782105, PubMed : 30808760). Has antimicrobial activity against a wide range of bacteria, including Gram-negative E.coli, P.aeruginosa and S.typhimurium, and Gram-positive E.aerogenes, S.aureus, B.cereus, E.faecium and L.monocytogenes (PubMed : 12021776, PubMed : 15616305, PubMed : 19589339, PubMed : 22359618, PubMed : 22573326, PubMed : 25354318, PubMed : 30808760). Confers resistance to intestinal infection by S.typhimurium (PubMed : 12660734). Exhibits antimicrobial activity against enteric commensal bacteria such as B.adolescentis, L.acidophilus, B.breve, L.fermentum, B.longum and S.thermophilus (PubMed : 25354318). Binds to bacterial membranes and causes membrane disintegration (PubMed : 25782105). Induces the secretion of the chemokine IL-8 by intestinal epithelial cells (PubMed : 19589339). Binds to B.antracis lef/lethal factor, a major virulence factor from B.anthracis, and neutralizes its enzymatic activity (PubMed : 22573326).. (Microbial infection) Acts as a target for S.flexneri infection by binding to the bacterium, possibly via bacterial surface proteins, and thereby augmenting infectivity via enhanced bacterial adhesion and invasion of epithelial cells and tissues. See full target information DEFA5
Category Paths
- Products>Primary Antibodies>IHC Antibodies
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