Anti-alpha smooth muscle Actin antibody,Abcam,AB5694

Anti-alpha smooth muscle Actin antibody (ab5694) is a rabbit polyclonal antibody and is validated for use in IHC-P and WB. Anti-alpha smooth muscle Actin antibody (ab5694) was first used in a scientific publication in 1985 and has been cited over 3004 times in peer reviewed journals. It's performance in Western blot, immunofluorescence and IHC in human, mouse and rat samples is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-alpha smooth muscle Actin antibody (ab5694) has high sensitivity and specificity. Anti-alpha smooth muscle Actin antibody (ab5694) has 150 independent reviews from customers. Anti-alpha smooth muscle Actin antibody (ab5694) specifically detects alpha smooth muscle Actin (UniProt ID: P62736; Molecular weight: 42kDa) and is sold in 100 µg selling sizes. Alpha-Smooth Muscle Actin (α-SMA) is a critical protein involved in smooth muscle contraction, encoded by the ACTA2 gene. Predominantly found in vascular smooth muscle cells, α-SMA plays a vital role in fibrogenesis and wound healing. It is often used as a marker for myofibroblast formation, which are specialized cells that contribute to tissue repair and fibrosis. The expression of α-SMA is associated with the activation of myofibroblasts, making it an important indicator in studies of fibrosis and other related conditions.

Host

Rabbit

Reactivity

Mouse, Human

Application

IHC-P, WB

Platform ID

BAB888141747

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-alpha smooth muscle Actin antibody
Cat. No.AB5694
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationIHC-P, WB
ClonalityPolyclonal
Concentration0.2 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human ACTA2. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. See full target information ACTA2

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