Anti-beta 2 Microglobulin antibody [3F9-2C2],Abcam,AB54810

This product was changed from ascites to tissue culture supernatant on 22/03/2019. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.

Host

Mouse

Reactivity

Human

Application

WB, IHC-P

Platform ID

BAB161355599

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-beta 2 Microglobulin antibody [3F9-2C2]
Cat. No.AB54810
HostMouse
IsotypeIgG2b
ReactivityHuman
ApplicationWB, IHC-P
ClonalityMonoclonal
Clone Number3F9-2C2
ImmunogenRecombinant Full Length Protein corresponding to Human B2M.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed : 25356553). See full target information B2M

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