Anti-beta 2 Microglobulin antibody [B2M/961],Abcam,AB215889

Host

Mouse

Reactivity

Human

Application

Flow Cyt, ICC, IHC-P, WB

Platform ID

BAB598924316

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-beta 2 Microglobulin antibody [B2M/961]
Cat. No.AB215889
HostMouse
IsotypeIgG2b
ReactivityHuman
ApplicationFlow Cyt, ICC, IHC-P, WB
ClonalityMonoclonal
Clone NumberB2M/961
Concentration0.2 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human B2M.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed : 25356553). See full target information B2M

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.