Anti-beta 2 Microglobulin antibody [B2M/961] - BSA and Azide free,Abcam,AB212756

Host

Mouse

Reactivity

Human, Primates

Application

IHC-P

Platform ID

BAB911430563

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-beta 2 Microglobulin antibody [B2M/961] - BSA and Azide free
Cat. No.AB212756
HostMouse
IsotypeIgG2b
ReactivityHuman, Primates
ApplicationIHC-P
ClonalityMonoclonal
Clone NumberB2M/961
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human B2M.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed : 25356553). See full target information B2M

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