Anti-beta 2 Microglobulin antibody,Abcam,AB6608
The antibody reacts with b2-microglobulin isolated from human urine showing a 12.8 kDa band under non-reducing condition of SDS-PAGE.
Host
Rabbit
Reactivity
Human
Application
WB, ICC/IF
Platform ID
BAB723886834
Abcam
Contact
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Product Specifications
Scientific Background
Specifications
NameAnti-beta 2 Microglobulin antibody
Cat. No.AB6608
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationWB, ICC/IF
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenNative Full Length Protein corresponding to Human B2M.
PurityIon exchange chromatography
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.01% Sodium azide Constituents: 0.88% Sodium chloride, 0.424% Potassium phosphate solution
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed : 25356553). See full target information B2M
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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