Anti-beta 2 Microglobulin antibody [D2E9],Abcam,AB198486
This product was changed from ascites to tissue culture supernatant on 12/12/2018. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.
Host
Mouse
Reactivity
Human
Application
ICC/IF, Flow Cyt
Platform ID
BAB536443057
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
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Product Specifications
Scientific Background
Specifications
NameAnti-beta 2 Microglobulin antibody [D2E9]
Cat. No.AB198486
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationICC/IF, Flow Cyt
ClonalityMonoclonal
Clone NumberD2E9
ImmunogenNative Full Length Protein corresponding to Human B2M.
PurityAffinity purification Protein G
Appearance/FormLyophilized
ShippingBlue Ice
FormulationpH: 7.2 Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed : 25356553). See full target information B2M
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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