Anti-beta 2 Microglobulin antibody [EPR21752-214],Abcam,AB218230

What is this antibody validated in? Anti-beta 2 Microglobulin antibody [EPR21752-214] (ab218230) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunohistochemistry (IHC-P) in Human, Mouse, Rat samples. What is the molecular weight of beta 2 Microglobulin? Anti-beta 2 Microglobulin [EPR21752-214] (ab218230) specifically detects a band for beta 2 Microglobulin (UniProt: P61769) at a molecular weight of 14kDa. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-beta 2 Microglobulin antibody [EPR21752-214] (ab218230) has been confirmed by Western blot testing in B2M Knockout HEPG2 cell line, ab266828 . Other related products We have a range of other formats of antibody clone [EPR21752-214] also available for your convenience: ab218230, Carrier free - ab237032 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

WB, IP, Flow Cyt (Intra), IHC-P

Platform ID

BAB723986786

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-beta 2 Microglobulin antibody [EPR21752-214]
Cat. No.AB218230
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationWB, IP, Flow Cyt (Intra), IHC-P
ClonalityMonoclonal
Clone NumberEPR21752-214
Concentration0.522 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed : 25356553). See full target information B2M

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