Anti-beta 2 Microglobulin antibody [rB2M/961] - BSA and Azide free,Abcam,AB236274

Host

Mouse

Reactivity

Human

Application

IHC-P, Protein Array

Platform ID

BAB661505527

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-beta 2 Microglobulin antibody [rB2M/961] - BSA and Azide free
Cat. No.AB236274
HostMouse
IsotypeIgG2b
ReactivityHuman
ApplicationIHC-P, Protein Array
ClonalityMonoclonal
Clone NumberrB2M/961
ImmunogenRecombinant Full Length Protein corresponding to Human B2M.
PurityAffinity purification Protein A/G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed : 25356553). See full target information B2M

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