Anti-beta Actin antibody [EPR21241] - Loading Control,Abcam,AB213262
What is this antibody validated in? Anti-beta Actin antibody [EPR21241] (ab213262) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse samples. What is the molecular weight of beta Actin? Anti-beta Actin [EPR21241] (ab213262) specifically detects a band for beta Actin (UniProt: P60709) at a molecular weight of 42kDa. Trusted by the scientific community Anti-beta Actin [EPR21241] (ab213262) was first used in a scientific publication in 2018 and has been cited over 10 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-beta Actin antibody [EPR21241] (ab213262) has been confirmed by Western blot testing in ACTB Knockout HAP1 cells.
Host
Rabbit
Reactivity
Mouse, Human
Application
ICC/IF, WB
Platform ID
BAB724086738
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells (PubMed : 25255767, PubMed : 29581253). Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction (PubMed : 29581253). In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA (PubMed : 29925947). Plays a role in the assembly of the gamma-tubulin ring complex (gTuRC), which regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments (PubMed : 39321809, PubMed : 38609661). Part of the ACTR1A/ACTB filament around which the dynactin complex is built (By similarity). The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules (By similarity). See full target information ACTB
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- Products>Primary Antibodies>Monoclonal Antibodies
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